James Chan1, Matthew Barnett2, Dale Bowie3, Clare Bradley4, Tane Bradley4, David Burritt5, Eleanor Cheong1, Santanu Deb-Choudhury6, David Everett7, Stephen Haines6, Linn Hoffmann5, Jeremy Lim8, Amber Milan2, Niranjan Nagarajan9, Geraldine Oh1, Elizabeth Rettedal10, Alastair Ross6, Katja Schweikert5, Lee Tane11, Jonathan Teo9, Kai Yee Toh8 and Linda Samuelsson7
1Singapore Institute of Food and Biotechnology Innovation, A*STAR, Singapore, 2Physiology & Health Team, AgResearch Ltd, Auckland, New Zealand, 3Ideas 2 Plate, Wellington, New Zealand, 4AgriSea NZ Seaweed Ltd, Paeroa, New Zealand, 5Department of Botany, University of Otago, Dunedin, New Zealand, 6Proteins & Metabolites Team, AgResearch Ltd, Lincoln, New Zealand, 7Food Chemistry & Structure Team, AgResearch Ltd, Palmerston North, New Zealand, 8AMILI Pte Ltd, Singapore, 9Genome Institute of Singapore, A*STAR, Singapore, 10Food Informatics Team, AgResearch Ltd, Palmerston North, New Zealand, 11Māori Research Partnerships, AgResearch Ltd, Hamilton, New Zealand,
Correspondence: Linda Samuelsson, linda.samuelsson@agresearch.co.nz
New knowledge about human digestion, nutritional availability, flavour and health benefits of seaweed as a whole food is generated through this collaborative project. Several protein-rich seaweed species in their raw form, including Undaria pinnatifida and Ulva sp., from New Zealand and/or Singapore are characterised from nutritional and food safety perspectives, and environmental factors affecting seaweed composition are investigated. Seaweed will then be prepared into delicious food products using innovative cooking methods for comparison with extensively processed seaweed to identify benefits of the whole food concept: Raw, cooked, and extensively processed seaweed will be digested in a state-of-the art in vitro digestion system representing the stomach, small and large intestines. The latter will contain extracted NZ or Singaporean human gut microbiota to account for differences in diet, and thus in gut microbiota and ability to digest seaweed, between these two populations. Processes through different stages of digestion will be tracked using advanced proteomic, peptidomic and metabolomic techniques and microbiota composition. Metagenomic and metabolomic tools will monitor the longitudinal trajectory of both NZ and Singaporean microbiota and metabolite products during digestion. Results will be integrated to obtain mechanistic insight into seaweed cooking techniques, digestion and nutritional benefits to the consumer, both directly and through the impact of the microbiota, and will inform a human clinical trial.
This presentation includes an overview of the project, results to date and planned next steps. The knowledge generated in this project will inform product development of the next generation of seaweed-based protein-rich foods.