Kevin Engholdt1, Gitte Jensen2, Kathleen Benson2
1Infinitum Health, LLC, Scottsdale, AZ, USA, 2Natural Immune Systems Labs, Everett, WA
The products from Infinitum Health portfolio have garnered dramatic results from consumers causing an intense public demand. One of their flagship products, Infinimin®, has collected numerous positive testimonials from patients with diverse health problems. The most common testimonies involve cancers and based upon these testimonials, a preclinical study using four cancer cell lines was performed. To understand more about the mechanisms by which these customers are stating benefits, we designed an MTT Screening Assay using four cancer cell lines to aid in understanding cell viability and apoptosis. The effects of Infinimin® on cancer cell viability was tested on the following 4 cell lines; A-172, glioblastoma; A-375, malignant melanoma; A-549, lung; and DU-145, prostate. The test product was prepared for addition to cell cultures in vitro in the following manner; 0.5g dry product was added to 5ml of phosphate-buffered saline (PBS) and 0.5g dry product was added to 5mL 95% ethanol (EtOH). Statistically significant reductions (p: <.05) of cell viability were seen for all 4 cancer cell lines following treatment with Infinimin® (PBS). The decrease in Glioblastoma and Prostate Carcinoma cell viability following treatment with Infinimin® (PBS) was dose-dependent and extended across a broad dose range. This is a first step understanding how consumption of Infinimin® supports health. In the case of cancers, the data here suggest that some compounds in Infinimin® could have a direct synergistic effect on reducing the growth of cancer cells. Moreover, the consumption of Inifinimin® may also support the defense and anti-cancer properties of the immune system. Based on the ingredients in Infinimin®, particularly three seaweed species, three mushroom species, acai berry, and a base multivitamin panel, we would expect to see immune activating effects but not as broad as impacting four different cancer physiologies. As shown, there are no toxic effects with this product, however, further research is needed in the preclinical space as well as clinical trials to validate efficacy and understanding of the mechanism of action of these extracts and how they are reducing cancer growth.